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KMID : 0861420120160020035
Korean Journal of Nuclear Medicine Technology
2012 Volume.16 No. 2 p.35 ~ p.43
The Study of Usefulness of Metal Artifact Reduction Algorithm and Artifacts Caused by Metallic Hip Prosthesis on PET/CT
Park Min-Soo

Ham Joon-Chul
Cho Yong-In
Kang Chun-Koo
Park Hoon-Hee
Lim Han-Sang
Lee Chang-Ho
Abstract
Purpose:PET/CT performed CT-based attenuation correction generates the beam hardening artifact by metallic
implant. The attenuation correction causes over or underestimate of the area adjacent to metallic hip prosthetic
material and change of 18F-FDG uptake. Also, the image quality and the diagnosability on genitourinary disease
are reduced. Therefore, this study will evaluate the usefulness of MAR (Metal Artifact Reduction) algorithm
method to improve the image quality on PET/CT.

Materials and Methods:PET/CT was performed by fixing hip prosthesis in SPECT/PET phantom. In PET images with and Without MAR algorithm, the Bright streak, Dark streak, Metal region and Background area that appeared on CT were confirmed, and the change of each SUV (standardized uptake value) was analyzed. Also, in 15 patients who underwent total hip arthroplasty, each MAR algorithm and Without MAR algorithm and non attenuation correction was evaluated.

Results: In PET imageWithout MAR algorithm, SUV of Bright streak region was 0.98¡¾0.48 g/ml; Dark streak region was 0.88¡¾0.02g/ml; Metal region was 0.24¡¾0.16 g/ml, Background area was 0.91¡¾0.18 g/ml. In SUV of PET image with MARalgorithm, Bright streak region was 0.88¡¾0.49 g/ml, Dark streak region was 0.63¡¾0.21 g/ml, Metal region was
0.06¡¾0.07 g/ml, Background was 0.90¡¾0.02 g/ml. SUV generally decreased when applying MAR algorithm. In
PET image Without MAR algorithm, SUVs of Bright region were higher than those measured in the
Background, and it was false positive uptake. But, in PET image with MAR algorithm, SUVs of Bright region
were similar to the Background, and false positive uptake disappeared.

Conclusion: MAR algorithm could reduce an increase of 18F-FDG uptake due to attenuation correction in the hip surrounding tissue. However, decrease of SUV in Dark streak region should be considered in the future. Therefore, this study propose that the diagnostic accuracy can be improved in genitourinary diseases adjacent to metallic hip prosthesis, if provided PET images with and Without MAR algorithm, and non attenuation correction images at the same time.
KEYWORD
MAR (Metal Artifact Reduction) algorithm, Hip Prosthesis, Beam Hardening Artifact
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